Small dense low density lipoprotein-cholesterol and cholesterol ratios to predict arterial stiffness progression in normotensive subjects over a 5-year period

Li, Gang; Wu, Hui-kun; Wu, Xiao-wei; Cao, Zhe; Tu, Yuan-chao; Ma, Yi; Wang, Wei-qing; Cheng, Jian; Zhou, Zi-hua

doi:10.1186/s12944-018-0671-2

Lipids in Health and Disease

Table 2 PWV parameters, cholesterol parameters and ratios and inflammatory factors of subjects by PWV and hypertension progression

From: Small dense low density lipoprotein-cholesterol and cholesterol ratios to predict arterial stiffness progression in normotensive subjects over a 5-year period

Variables	non-PWV progression	PWV progression	p value	non-HT progression	HT progression	p value
Age(years)	38.5 ± 7.7	41.8 ± 7.7	< 0.001	38.6 ± 8.2	41.7 ± 5.2	< 0.001
Baseline PWV(m/s)	9.63 ± 0.58	11.18 ± 0.71	< 0.001	9.89 ± 0.79	9.99 ± 0.98	0.092
Follow-up PWV(m/s)	10.12 ± 0.67	12.70 ± 0.64	< 0.001	10.46 ± 1.10	11.17 ± 1.43	< 0.001
△PWV(m/s)	0.48 ± 0.27	1.52 ± 0.56	< 0.001	0.63 ± 0.49	0.87 ± 0.62	< 0.001
△SBP(mmHg)	3.11 ± 0.78	3.38 ± 0.85	0.205	2.75 ± 0.74	3.86 ± 0.81	< 0.01
△DBP(mmHg)	2.82 ± 0.69	3.63 ± 0.77	0.039	2.79 ± 0.58	3.81 ± 0.80	< 0.01
△PP(mmHg)	0.26 ± 0.08	0.27 ± 0.06	0.765	0.25 ± 0.09	0.28 ± 0.10	0.113
△MAP(mmHg)	3.08 ± 0.57	3.72 ± 0.61	0.032	2.88 ± 0.45	3.79 ± 0.57	< 0.01
TC(mmol/L)	4.81 ± 0.80	4.69 ± 0.67	0.086	4.80 ± 0.79	4.75 ± 0.75	0.515
TG(mmol/L)	1.58 ± 0.69	1.96 ± 0.83	< 0.001	1.64 ± 0.72	1.72 ± 0.81	0.276
LDL-C(mmol/L)	2.98 ± 0.79	2.96 ± 0.63	0.684	2.99 ± 0.77	2.95 ± 0.70	0.566
HDL-C(mmol/L)	1.20 ± 0.28	1.22 ± 0.29	0.352	1.21 ± 0.28	1.23 ± 0.32	0.469
sdLDL-C(mmol/L)	0.68 ± 0.28	0.77 ± 0.25	< 0.001	0.70 ± 0.27	0.69 ± 0.31	0.661
ApoB(g/L)	0.94 ± 0.25	0.96 ± 0.27	0.301	0.94 ± 0.25	0.96 ± 0.28	0.516
ApoA-1(g/L)	1.23 ± 0.30	1.23 ± 0.33	0.916	1.23 ± 0.30	1.21 ± 0.32	0.523
TC/HDL-C	4.21 ± 1.23	4.02 ± 1.09	0.081	4.19 ± 1.18	4.14 ± 1.37	0.709
TG/HDL-C	1.39 ± 0.72	1.69 ± 0.83	< 0.001	1.43 ± 0.72	1.51 ± 0.89	0.233
LDL-C/HDL-C	2.62 ± 0.95	2.55 ± 0.82	0.398	2.61 ± 0.91	2.59 ± 1.02	0.794
SdLDL-C/HDL-C	0.61 ± 0.34	0.66 ± 0.28	0.063	0.62 ± 0.31	0.61 ± 0.40	0.857
ApoB/ApoA-1	0.81 ± 0.31	0.84 ± 0.32	0.357	0.81 ± 0.31	0.84 ± 0.32	0.338
TNF-α(pg/ml)	3.02 ± 0.82	3.13 ± 0.80	0.153	3.05 ± 0.82	2.99 ± 0.83	0.492
IL-6(pg/ml)	2.69 ± 1.18	2.53 ± 1.12	0.126	2.67 ± 1.17	2.63 ± 1.18	0.738
hs-CRP(mg/L)	0.74 ± 0.19	0.84 ± 0.22	0.298	0.75 ± 0.16	0.84 ± 0.21	0.350

Back to article page

ISSN: 1476-511X

Contact us

General enquiries: journalsubmissions@springernature.com