Skip to main content

Table 3 Fatty acid composition of triglyceride in periuterine adipose tissue of Fischer 344 rats

From: Chemotherapy diminishes lipid storage capacity of adipose tissue in a preclinical model of colon cancer

Fatty acids (% total)

REF

TUM

1- Cycle 2- Cycles

C16:0

20.6 ± 0.5a

19.7 ± 0.3a

20.0 ± 0.4a

17.9 ± 0.7b

C16:1

3.9 ± 0.2a

3.6 ± 0.1a

3.4 ± 0.2a

2.6 ± 0.3b

C18:0

6.0 ± 0.3a

6.9 ± 0.2a

6.7 ± 0.1a

7.9 ± 0.4a

C18:1

41.3 ± 2.1a

42 ± 1a

41.3 ± 0.6a

44.3 ± 0.9a

C18:2n6

22.3 ± 1.6a

22.0 ± 0.7a

23.4 ± 0.5a

22.5 ± 0.4a

C18:3n3

1.6 ± 0.1a

1.7 ± 0a

1.3 ± 0b

1.2 ± 0.1b

C20:4n6

0.8 ± 0.1a

0.7 ± 0a

0.6 ± 0a

0.6 ± 0a

C20:5n3

ND

ND

ND

ND

C22:6n3

0.4 ± 0.1a

0.4 ± 0a

0.3 ± 0a

0.3 ± 0a

ΣSFA

28.3 ± 0.3a

28.2 ± 0.2a

28.3 ± 0.3a

27.3 ± 0.3a

ΣMUFA

45.7 ± 2a

46.1 ± 1a

45.2 ± 0.6a

47.4 ± 0.7a

Σn-6/n-3

11.2 ± 0.6a

10.3 ± 0.2a

13.6 ± 0.5b

14.7 ± 0.7b

Σn-6

23.8 ± 1.7a

23.4 ± 0.8a

24.7 ± 0.5a

23.7 ± 0.4a

Σn-3

2.2 ± 0.3a

2.3 ± 0.1a

1.8 ± 0.1b

1.6 ± 0.1b

  1. Triglyceride fatty acids in periuterine adipose tissue of Fischer 344 rats bearing the Ward colorectal carcinoma receiving 1- or 2- cycles of chemotherapy. Healthy rats were used a reference for comparison (REF). Mean ± SEM, Kruskall test was used to determine significant differences between groups. Different superscripts (a, b) indicate significant differences between groups (P < 0.05); (n = 6–8/group). Abbreviations: SFA, saturated fatty acids; MUFA, monounsaturated fatty acids; PUFA, polyunsaturatsed fatty acids; REF, Reference; TUM, Tumour-bearing; ND, not determined