Effect of low and high HDL-C levels on the prognosis of lupus nephritis patients: a prospective cohort study

Table 2 Multivariate logistic regression models for the risk factors of low HDL-C and high HDL-C

Risk factors	OR	95% CI	P
Low HDL-C (n = 401)
Disease duration, months	0.99	0.99–1.00	0.010
eGFR, 10 ml/min/1.73m²	0.96	0.92–0.99	0.018
Total cholesterol, mmol/L	0.59	0.47–0.75	<0.001
Triglyceride, mmol/L	1.89	1.53–2.32	<0.001
LDL-C, mmol/L	1.17	0.89–1.55	0.260
SLEDAI	1.02	0.98–1.05	0.438
Hypoalbuminemia	1.41	0.91–2.18	0.121
High HDL-C (n = 128)
Total cholesterol, mmol/L	1.59	1.20–2.10	0.001
Triglyceride, mmol/L	0.57	0.42–0.77	<0.001
Immunosuppressive treatment	1.90	1.13–3.20	0.016

Note: Reference category is intermediate HDL-C (n = 246). The significant variates in univariate analysis were forced into the multivariate models and other variables excluding HDL-C levels listed in Table 1 were selected into the multivariate models by the forward method (entry: 0.1, removal: 0.2). Biopsy data were not included in the model
OR: odds ratio; 95% CI: 95% confidence interval. SLEDAI Systemic lupus erythematosus disease activity index

ISSN: 1476-511X