Parameters | Total (n = 775) | Low HDL-C (n = 401) | Intermediate HDL-C (n = 246) | High HDL-C (n = 128) | P |
---|---|---|---|---|---|
Age, years | 31.2 ± 13.1 | 30.9 ± 13.6 | 31.8 ± 12.7 | 31.3 ± 12.2 | 0.666 |
Gender (female %) | 645 (83.2) | 328(81.8) | 208 (84.6) | 109 (85.2) | 0.538 |
Smoking (%) | 23 (3.0) | 16 (4.0) | 5 (2.0) | 2 (1.6) | 0.201 |
Weight, kg | 53.8 ± 10.3 | 53.8 ± 11.2 | 53.3 ± 9.2 | 54.3 ± 9.3 | 0.675 |
Disease duration, months | 3 (1, 16) | 2 (1, 11) | 6 (1, 32) | 4 (1, 21) | <0.001 |
eGFR, ml/min/1.73m2 | 81.8 (46.2, 125.0) | 71.5 (38.5, 113.3) | 87.5 (52.9, 127.0) | 109.9 (67.6, 135.6) | <0.001 |
24-h proteinuria, g | 1.7 (0.8, 3.2) | 1.7 (0.8, 3.3) | 1.6 (0.8, 3.2) | 1.8 (0.7, 3.1) | 0.957 |
Total cholesterol, mmol/L | 6.11 ± 2.47 | 5.52 ± 2.42 | 6.53 ± 2.36 | 7.12 ± 2.34 | <0.001 |
Triglyceride, mmol/L | 2.50 ± 1.86 | 2.90 ± 2.12 | 2.15 ± 1.38 | 1.89 ± 1.45 | <0.001 |
HDL-C, mmol/L | 1.09 ± 0.49 | 0.72 ± 0.18 | 1.27 ± 0.14 | 1.92 ± 0.39 | <0.001 |
LDL-C, mmol/L | 3.59 ± 1.82 | 3.13 ± 1.66 | 3.99 ± 1.79 | 4.24 ± 1.96 | <0.001 |
SLEDAI | 14 (11, 18) | 16 (12, 18) | 14 (10, 18) | 12 (10, 16) | <0.001 |
Diabetes mellitus (%) | 55 (7.1) | 31 (7.7) | 21 (8.5) | 3 (2.3) | 0.067 |
Hypertension (%) | 307 (39.6) | 159 (39.7) | 102 (41.5) | 46 (35.9) | 0.584 |
Hypoalbuminemia | 471 (60.8) | 261 (65.1) | 139(56.5) | 71(55.5) | 0.038 |
Global sclerosisa (%) | 224 (42.3) | 105 (38.6) | 79 (47.3) | 40 (44.0) | 0.188 |
Crescentsa (%) | 275 (51.9) | 144 (52.9) | 84(50.3) | 47(51.6) | 0.864 |
Interstitial inflammationa (%) | 390 (73.6) | 211(77.6) | 115(68.9) | 64(70.3) | 0.098 |
Tubular atrophya(%) | 301 (56.8) | 152 (55.9) | 100 (59.9) | 49 (53.8) | 0.588 |
Interstitial fibrosisa(%) | 307 (57.9) | 153 (56.3) | 100 (59.9) | 54 (59.3) | 0.723 |
Corticosteroid treatment (%) | 751 (96.9) | 387 (96.5) | 240 (97.6) | 124 (96.9) | 0.755 |
Immunosuppressive treatment (%) | 468 (60.4) | 241 (60.1) | 137 (55.7) | 90 (70.3) | 0.023 |
Lipid-lowering treatment (%) | 163 (21.0) | 81 (20.2) | 53 (21.5) | 29 (22.7) | 0.815 |