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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: ALA/LA ameliorates glucose toxicity on HK-2 cells by attenuating oxidative stress and apoptosis through the ROS/p38/TGF-β1 pathway

Fig. 6

TGF-β1, p-p38 and p38 expression, assessed by western blot, in high glucose induced HK-2cells with ALA/LA and/or SB203580 intervention (100 μM). a Protein expression of TGF-β1 and p38 in high glucose induced HK-2cells with ALA/LA and/or SB203580 by Western blot. b The effects of SB203580 on TGF-β1, p-p38 and p38 expression in high glucose induced HK-2cells. c The effects of ALA/LA and SB203580 (the inhibitor of p38) on TGF-β1, p-p38 and p38 expression in high glucose induced HK-2cells.The intensity of the bands was quantified by densitometry analysis and normalized with corresponding GADPH. Values are expressed as the mean ± SD. Bars without a common superscript symbol indicate significant differences among groups at P < 0.05. N: normal control group; G: high glucose model group; A, L, E: ALA/LA/EPA intervention group at dose of 100 μM; M: mixture of ALA and LA intervention group at dose of 100 μM with ALA/LA ratio of 1:4

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