Fig. 3From: Sodium butyrate promotes apoptosis in breast cancer cells through reactive oxygen species (ROS) formation and mitochondrial impairmentSodium butyrate induced cell cycle arrest in breast cancer cells. Cells were treated with sodium butyrate (1, 5, 10 mM) for 48 h and cell cycle distribution were analyzed by flow cytometry using PI staining for MCF-7 (a), MDA-MB-468 (b) and MCF-10A (c).The accumulation of cells in sub-G1 phase was increased significantly in both cell lines. Data represent Mean ± SD of three separate experiments. Statistical differences between different groups were analyzed by ANOVA (* = P < 0.05, ** = P < 0.01, *** = P < 0.001)Back to article page