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Table 1 Study design of the experiment

From: Lowering effects of aspirin eugenol ester on blood lipids in rats with high fat diet

Groups

Food

Drug

Dosage

Concentration

Control

SRD

--

--

--

Model

HFD

--

--

--

CMC-Na

HFD

CMC-Na

20 mg/kg

5 mg/mL

Statin

HFD

Simvastatin

10 mg/kg

2.5 mg/mL

AEE Low

HFD

AEE

18 mg/kg

4.5 mg/mL

AEE Mid

HFD

AEE

36 mg/kg

9 mg/mL

AEE High

HFD

AEE

54 mg/kg

13.5 mg/mL

  1. Rats were divided into seven groups. Control group was received SRD and the rest groups were received HFD, respectively. Based on the individual weekly body weight, rats were given with different drug suspension volume. CMC-Na as a vehicle was used in control group. Simvastatin was designed as positive drug. Different dose of three levels of AEE were administrated in the study. The administration period was 6 weeks and then blood lipids were analyzed
  2. AEE aspirin eugenol ester, SRD standard rat diet, HFD high fat diet