From: MiR-106b exhibits an anti-angiogenic function by inhibiting STAT3 expression in endothelial cells
microRNAs | Biological function | Target genes | References |
---|---|---|---|
miR-93 | Preventing the progression of diabetic nephropathy | VEGF | [22] |
miR-106b ~ 25 | Inhibiting cell-cycle arrest and apoptosis | p21,Bim | |
miR-106b | Impairing cellular cholesterol efflux and increasing the levels of secreted amyloid β | ABCA1 | [24] |
miR-106b,93 | Inhibiting brown adipocyte differentiation | [25] | |
miR-106b ~ 25 | Inhibiting apoptosis and promoting tube formation | PTEN | [16] |
miR-25 | Suppressing Cdk inhibitors and promoting cell proliferation | p57Kip2 | [23] |
miR-106b | Inhibiting cell cycle arrest and promoting cell proliferation | E2F1,E2F3 | [26] |
miR-106b | Activating p73 apoptotic signaling in Chronic Lymphocytic Leukemia cells | ITCH | [27] |
miR-106b | Maintaining the structural homeostasis of developing lung epithelium | MAPK14,STAT3 | [17] |
miR-93 | Inducing embryonic stem cell differentiation | STAT3 | [28] |