Control group | HFD group | Acipimox group | |||||||
---|---|---|---|---|---|---|---|---|---|
Weeks | 8 w | 16 w | 24 w | 8 w | 16 w | 24 w | 8 w | 16 w | 24 w |
Weight (g) | 419.7 ± 8.6 | 500.5 ± 9.8 | 582.6 ± 16.5 | 470.2 ± 17.8 | 646.2 ± 15.5** | 690.5 ± 29.5* | 456.0 ± 16.6 | 615.3 ± 22.2** | 682.7 ± 20.2* |
Visceral fat (g) | 14.04 ± 0.79 | 17.43 ± 1.26 | 20.06 ± 1.78 | 24.71 ± 1.04** | 52.97 ± 4.16** | 73.44 ± 5.15**# | 24.86 ± 0.67** | 46.03 ± 4.22** | 56.58 ± 3.39** |
Visceral fat/weight (%) | 3.5 ± 0.2 | 3.4 ± 0.3 | 3.6 ± 0.3 | 5.3 ± 0.3** | 8.3 ± 0.7** | 10.9 ± 0.5**## | 5.5 ± 0.4** | 7.5 ± 0.7** | 8.7 ± 0.4** |
Liver/body weight (%) | 2.7 ± 0.1 | 2.5 ± 0.1 | 2.6 ± 0.1 | 3.2 ± 0.1* | 3.3 ± 0.2* | 3.1 ± 0.1** | 3.1 ± 0.1* | 3.1 ± 0.1* | 3.0 ± 0.1* |