Model | AUC ± SE | n |
---|
(mg.dl−1.min) | male/female |
---|
Aged-NTg | 10933 ± 1570 (4) | 4/0 |
Aged-CETP | 11737 ± 1069 (7) | 7/0 |
ApoCIII−/+
| 22777 ± 3238 (4) | 3/1 |
ApoCIII−/+ /CETP−/+
| 25114 ± 9466 (3) | 1/2 |
LDLr−/+
| 15920 ± 2587 (4) | 0/4 |
LDLr−/+/CETP+/−
| 12951 ± 407 (5) | 2/3 |
- Area under the curve (AUC) of oral glucose tolerance test in aged (18 month old), apo CIII transgenic and LDL receptor deficient (LDLr−/+) mice expressing or not CETP, fasted for 12 h. At time zero, mice received a glucose dose of 1.5 g/kg body weight by gavage. Samples for glucose determination were collected from the tail tip at 0, 15, 30, 60 and 120 min. Values are expressed as mean ± SE (n: male and female pooled data). Student’s t test for all comparisons: non-significant