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Table 2 Effects of diet supplementation with FSC-S and FSC-SpEt on hepatic lipids and GLU in normal and experimental hypercholesterolemic (HCL) mice

From: A comparative study between Wuweizi seed and its post-ethanol extraction residue in normal and hypercholesterolemic mice

Groups

Dose

TC

TG

GLU

(%, w/w)

(μmol/g)

(μmol/g)

(μmol/g)

Normal mice

    

ND

–

3.94 ± 0.11

7.14 ± 0.15

132.98 ± 3.13

ND/FSC-S

9

3.21 ± 0.09**

8.14 ± 0.31**

100.86 ± 2.80**

ND/FSC-SpEt

9

3.31 ± 0.13**

5.73 ± 0.18**

138.95 ± 3.83

ND/FF

0.05

1.61 ± 0.06**

3.54 ± 0.25**

95.37 ± 3.67**

HCL mice

    

ND

–

7.35 ± 0.08

6.82 ± 0.11

106.81 ± 3.83

HCBD

–

11.52 ± 0.55**

11.12 ± 0.82**

107.67 ± 2.88

HCBD/FSC-S

3

12.45 ± 0.39

13.05 ± 0.58

97.57 ± 2.35#

 

9

11.90 ± 0.05

13.35 ± 0.48#

84.48 ± 1.65##

HCBD/FSC-SpEt

3

11.59 ± 0.51

10.13 ± 0.43

102.84 ± 1.67

 

9

10.70 ± 0.47

9.70 ± 0.55

104.73 ± 1.67

HCBD/FF

0.05

7.02 ± 0.22##

6.34 ± 0.15##

65.67 ± 2.14##

  1. Experimental details were described in Table 1. Mice were fed with ND and HCBD without or with FSC-S, FSC-SpEt, or FF supplementation. Ten days after supplementation, hepatic TC, TG and GLU contents were determined. Values given are the means ± SEM, with n = 10. * P < 0.05, ** P < 0.01 vs ND; # P < 0.05, ## P < 0.01 vs HCBD. Statistical significant differences were determined using a one-way ANOVA followed by Dunnett’s multiple comparisons test or post-hoc analysis