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Table 5 Logistic regression of CVD and allele 4 association in MetS (+) and MetS (−) patients adjusted for age, sex, smoking, DM, Col, HDL-C and LDL-C

From: Diversity of Apolipoprotein E genetic polymorphism significance on cardiovascular risk is determined by the presence of Metabolic Syndrome among hypertensive patients

Metabolic syndrome (+)

   

CVD

OR

CI

P

  Adjusted for E4 allele

1.96

1.03 - 3.70

0.03

  Adjusted for E4 allele, age

2.28

1.16 – 4.47

0.01

  Adjusted forE4 allele, age, sex

2.28

1.16 – 4.49

0.01

  Adjusted for E4 allele, age, sex, smoking

2.45

1.23 – 4.87

0.01

  Adjusted for E4 allele, age, sex, smoking, DM

2.45

1.22 – 4.90

0.01

  Adjusted for E4 allele, age, sex, smoking, DM, Col

2.37

1.16 - 4.81

0.01

  Adjusted for E4 allele, age, sex, smoking, DM, Col, HDL-C

2.38

1.16 - 4.87

0.01

  Adjusted for E4 allele, age, sex, smoking, DM, Col, HDL-C, LDL-C

2.23

1.08 - 4.59

0.02

Metabolic syndrome (−)

   

CVD

OR

CI

P

  Adjusted for E4 allele

0.21

0.04 – 0.96

0.04

  Adjusted for E4 allele, age

0.19

0.04 – 0.90

0.03

  Adjusted for E4 allele, age, sex

0.18

0.04 – 0.87

0.03

  Adjusted for E4 allele, age, sex, smoking

0.20

0.04 – 0.97

0.04

  Adjusted for E4 allele, age, sex, smoking, DM

0.19

0.03 - 0.92

0.04

  Adjusted for E4 allele, age, sex, smoking, DM, Chol

0.17

0,03 - 0,83

0.02

  Adjusted for E4 allele, age, sex, smoking, DM, Chol, HDL-C

0.17

0.03 - 0.84

0.03

  Adjusted for E4 allele, age, sex, smoking, DM, Chol, HDL-C, LDL-C

0.19

0.03 - 1.00

0.05

  1. CVD: cardiovascular disease; DM: diabetes mellitus; Chol: total cholesterol, HDL-C: HDL-cholesterol; LDL-C: LDL-cholesterol.