Lipids in Health and Disease

Table 7 Association of Tanis SNPs with LDL-C in Han and Uygur population

From: Genetic variation in Tanis was associated with elevating plasma triglyceride level in Chinese nondiabetic subjects

		Mean LDL-C level			Model 1‡			Model 2§
	Wild/Rare allele	Homozygous for rare allele	Heterozygous	Homozygous for wild allele	P Rec*	P Dom†	P Add^※	P Rec*	P Dom†	P Add^※
Han
rs12910524	C/T	2.55 ± 0.93	2.61 ± 0.79	2.72 ± 0.77	0.091	0.014	0.032	0.126	0.034	0.071
rs1384565	T/C	2.71 ± 0.90	2.70 ± 0.82	2.60 ± 0.78	0.043	0.502	0.128	0.119	0.731	0.295
rs2101171	T/C	2.38 ± 0.80	2.60 ± 0.74	2.68 ± 0.83	0.051	0.069	0.057	0.052	0.036	0.037
rs4965814	T/C	2.55 ± 0.84	2.68 ± 0.82	2.65 ± 0.77	0.970	0.070	0.163	0.869	0.151	0.339
Uygur
rs12910524	C/T	2.25 ± 0.80	2.52 ± 0.81	2.64 ± 0.78	0.003	0.022	0.004	0.005	0.025	0.007
rs1384565	T/C	2.02 ± 0.84	2.52 ± 0.78	2.56 ± 0.81	0.312	0.032	0.091	0.323	0.036	0.102
rs2101171	T/C	2.54 ± 0.79	2.53 ± 0.86	2.57 ± 0.80	0.905	0.951	0.988	0.888	0.945	0.990
rs4965814	T/C	2.40 ± 0.47	2.55 ± 0.82	2.58 ± 0.80	0.395	0.117	0.280	0.447	0.106	0.267

§Analysis of covariance adjusted for sex, age, smoking, alcohol drinking, and GLU; ‡Unadjusted model; *recessive model; †dominant model; ^※additive model.

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