Table 6 Effects of MLC on phase II antioxidant enzymes and DNA fragmentation
Group | GST (nM/mg protein) | GPx (nM/mg protein) | GR (nM/mg protein) | GSH (μM/g tissue) | QR (nM/mg protein) | %DNA Injuries |
|---|---|---|---|---|---|---|
Control | 150.23 ± 5.34g | 110.17 ± 4.46f | 198.34 ± 5.78e | 16.25 ± 1.11c | 99.90 ± 4.97f | 14.53 ± 2.57f |
Oil + DMSO | 157.17 ± 4.45g | 105.55 ± 4.55f | 204.73 ± 6.47e | 15.74 ± 1.31c | 107.03 ± 4.42f | 13.33 ± 2.24f |
CCl4 | 78.37 ± 4.33a | 63.33 ± 3.11a | 103.14 ± 4.66a | 9.60 ± 1.34a | 52.40 ± 4.16a | 57.50 ± 3.34a |
Sily + CCl4 | 133.67 ± 2.43f | 98.46 ± 2.22e | 179.56 ± 4.45d | 13.75 ± 0.32b | 89.14 ± 2.56e | 20.18 ± 3.73e |
100 mg/kg b.w. MFC + CCl4 | 120.54 ± 1.98c | 77.39 ± 2.92b | 166.07 ± 2.21c | 20.05 ± 0.90c | 75.25 ± 3.12d | 33.30 ± 0.25d |
200 mg/kg b.w. MFC + CCl4 | 124.12 ± 2.81e | 94.65 ± 2.16e | 170.68 ± 4.97d | 13.29 ± 0.46b | 82.56 ± 3.67d | 23.56 ± 2.36e |
MFC alone | 159.31 ± 3.21g | 112.40 ± 3.26f | 201.25 ± 4.12e | 17.59 ± 1.45c | 109.34 ± 2.23f | 12.55 ± 1.27f |