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Figure 3 | Lipids in Health and Disease

Figure 3

From: Activation of the mitochondrial ATP-sensitive K+ channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemia

Figure 3

MitoK ATP opening partially prevents enhanced apoptotic cell death in spleen mononuclear cells from HTG mice. HTG and WT cells (106 cells) were incubated for 20 min in binding buffer containing annexin V-FITC and 7-AAD, 10 μM DPI, at 37°C, in the absence (control) or presence of 1 mM 5HD or 10 μM GLYB, as described in the Materials and Methods Section. The results are expressed as means ± SEM, n = 5. *P < 0.01 vs. WT under same conditions; #P < 0.05 vs. HTG under control conditions.

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