Table 4 Genotypic lipid levels (Mean ± SD) of the -629C/A promoter polymorphism in the three ethnic populations for controls

Variables

CC

CA

AA

P

CC

CA

AA

P

CC

CA

AA

P

n = 49

n = 106

n = 46

R ² x100

n = 43

n = 74

n = 21

R ² x100

n = 32

n = 122

n =81

R ² x100

TC (mM)

5.58±1.13

5.88±1.22

6.08±1.28

P = 0.094

5.74±1.05

5.97±1.42

5.96±0.89

P = 0.809

5.69±0.99

5.96±1.29

5.63±1.21

P = 0.270

2.310

0.296

1.101

LDL-C(mM)

3.51±1.07

3.76±1.09

3.77±1.15

P = 0.370

3.68±0.95

3.76±1.46

3.74±1.05

P = 0.946

3.74±0.87

3.92±1.22

3.63±1.11

P = 0.354

1.000

0.083

0.872

HDL-C(mM)

1.21±0.26

1.25±0.32

1.35±0.33

P = 0.114

1.17±0.29

1.15±0.25

1.26±0.25

P = 0.433

1.02±0.37

0.99±0.24

1.07±0.27

P = 0.130

3.280

0.996

1.746

lnTG

0.53±0.48

0.57±0.45

0.63±0.45

P = 0.736

0.55±0.52

0.69±0.55

0.59±0.54

P = 0.614

0.54±0.58

0.72±0.48

0.55±0.55

P = 0.087

0.286

0.621

2.017

TG (mM)

1.70

1.77

1.88

  -

1.73

1.99

1.80

-

1.72

2.05

1.73

-

ApoA-1(mg/dl)

133.57±14.17

141.81±18.48

140.89±22.03

P = 0.029

124.50±19.38

127.78±17.14

134.48±16.39

P = 0.114

133.94±28.71

129.91±22.68

135.95±22.59

P = 0.201

3.350

3.238

1.409

ApoB(mg/dl)

111.43±30.09

116.13±28.86

120.56±32.60

P = 0.522

123.71±25.82

124.21±33.83

121.86±22.88

P = 0.850

124.41±28.28

134.53±33.71

122.61±31.47

P = 0.117

0.581

0.206

1.809

lnLp(a)

2.06±1.00

2.14±0.97

1.77±0.95

P = 0.218

2.13±0.99

2.19±0.92

2.03±0.71

P = 0.608

2.73±0.87

2.46±1.12

2.50±1.05

P = 0.524

1.865

1.095

0.722

Lp(a)(mg/dl)

7.84

8.49

5.89

8.39

8.97

7.58

-

15.28

11.68

12.07

-

Women

n = 331

Chinese

Malays

Indians

n = 173

n = 13

n = 145

Variables

CC

CA

AA

P

CC

CA

AA

P

CC

CA

AA

P

n = 44

n = 94

n = 35

R ² x100

n = 6

n = 6

n = 1

R ² x100

n = 26

n = 63

n = 56

R ² x100

TC (mM)

5.83±1.01

5.75±1.18

5.51±1.05

P = 0.583

5.78±1.37

5.32±0.81

4.85±0.00

P = 0.665

5.32±1.25

5.16±1.03

5.42±1.21

P = 0.104

0.562

7.841

2.776

LDL-C(mM)

3.62±1.01

3.57±1.18

3.21±1.04

P = 0.267

3.80±1.54

3.40±0.44

2.66±0.00

P = 0.620

3.41±1.06

3.26±0.96

3.43±1.14

P = 0.199

1.432

9.112

2.048

HDL-C(mM)

1.61±0.34

1.52±0.49

1.69±0.32

P = 0.103

1.42±0.17

1.33±0.38

1.92±0.00

P = 0.230

1.18±0.37

1.29±0.34

1.31±0.34

P = 0.121

2.380

25.481

2.779

lnTG

0.16±0.50

0.22±0.55

0.19±0.49

P = 0.709

0.05±0.60

0.11±0.57

-0.54±0.00

P = 0.604

0.20±0.69

0.18±0.50

0.26±0.48

P = 0.629

0.323

9.592

0.536

TG (mM)

1.17

1.25

1.21

1.05

1.12

0.58

1.22

1.20

1.30

ApoA-1(mg/dl)

151.86±23.78

150.69±24.82

148.72±21.16

P = 0.853

146.00±11.12

145.50±22.35

160.00±0.00

P = 0.230

134.44±28.66

139.32±24.63

147.57±27.20

P = 0.094

0.196

21.127

3.314

ApoB(mg/dl)

97.29±28.20

95.84±30.02

88.88±26.80

P = 0.520

100.33±23.96

102.50±10.05

85.00±0.00

P = 0.687

116.48±33.29

106.74±27.52

117.37±34.39

P = 0.014

0.689

7.222

4.429

lnLp(a)

2.53±1.23

2.41±1.02

2.45±1.07

P = 0.882

2.77±1.01

2.97±1.06

2.48±0.00

P = 0.909

2.90±1.02

2.75±0.98

3.00±0.89

P = 0.590

0.185

2.362

1.325

Lp(a)(mg/dl)

12.60

11.18

11.55

-

15.95

19.49

11.94

-

18.11

15.61

20.12

-