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Table 2 Fatty acid composition of erythrocyte membranes in patients with chronic respiratory diseases, mean ± SE

From: Modification of the fatty acid composition of the erythrocyte membrane in patients with chronic respiratory diseases

Fatty acids %

Healthy subjects n = 10

Patient with chronic bronchitis n = 15

Patients with chronic obstructive pulmonary disease n = 15

12:0

0.18 ± 0.01

0.35 ± 0.07**

 

14:0

0.39 ± 0.03

0.65 ± 0.12**

×××0.34 ± 0.01

15:0

0.17 ± 0.01

0.24 ± 0.04*

×××1.08 ± 0.01***

16:0

23.98 ± 1.28

22.32 ± 1.47

23.16 ± 0.28

16:1n-9

0.21 ± 0.05

0.27 ± 0.03

0.21 ± 0.05

16:1n-7

0.39 ± 0.03

0.51 ± 0.05*

0.53 ± 0.05

17:0

0.35 ± 0.02

0.27 ± 0.03

0.25 ± 0.03

18:0

13.40 ± 0.75

15.27 ± 0.52

16.78 ± 0.40*

18:1n-9

14.84 ± 0.84

14.86 ± 0.45

15.49 ± 0.73

18:1n-7

1.53 ± 0.08

1.33 ± 0.12

××1.76 ± 0.05

18:1n-5

0.32 ± 0.02

0.33 ± 0.08

0.36 ± 0.14

18:2n-6

15.75 ± 0.28

15.00 ± 0.16

×××12.21 ± 0.61**

18:3n-3

0.15 ± 0.02

0.22 ± 0.09

×××0.13 ± 0.03

20:0

0.15 ± 0.035

0.13 ± 0.04

×××0.46 ± 0.04***

20:1

0.34 ± 0.07

0.27 ± 0.07

0.23 ± 0.03

20:2n-6

0.25 ± 0.005

0.29 ± 0.03

0.26 ± 0.02

20:3n-6

1.59 ± 0.51

1.45 ± 0.17

1.70 ± 0.20

20:4n-6

12.95 ± 1.65

14.89 ± 0.79*

×××18.26 ± 0.50***

20:5n-3

1.23 ± 0.04

0.93 ± 0.09*

×××0.56 ± 0.06***

22:4n-6

2.37 ± 0.29

2.38 ± 0.22

×3.18 ± 0.31**

22:5n-6

0.37 ± 0.01

0.31 ± 0.04

×0.46 ± 0.07

22:5n-3

1.99 ± 0.02

1.88 ± 0.03*

1.82 ± 0.05*

22:6n-3

4.67 ± 0.85

6.09 ± 0.60

5.87 ± 0.39

Sum n-6

32.91 ± 0.10

34.32 ± 0.70*

36.07 ± 0.55**

Sum n-3

8.04 ± 0.12

9.12 ± 0.89

8.32 ± 0.42

20:4n-6/20:5n-3

10.52 ± 0.12

16.01 ± 1.3***

32.60 ± 2.8***

  1. Other fatty acids (10:0, 19:0, 22:0, 14:1, 22:1, 18:2n-5/9, and 20:3n-3) were present in trace amounts (< 0.1%) and are not included into the table.
  2. Asteriks indicate significant differences of fatty acid contents between patients with respiratory diseases and healthy subjects: * for р < 0.05; ** for р < 0.01; *** for р < 0.001; Asteriks indicate significant differences of fatty acid contents between patients with chronic bronchitis and with chronic obstructive pulmonary disease: × for р < 0.05; ×× for р < 0.01; ××× for р < 0.001.