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Table 1 Baseline Lipids, lipoproteins, and APO E genotype in 15 patients with triglyceride >500 mg/dl

From: Titrating lovaza from 4 to 8 to 12 grams/day in patients with primary hypertriglyceridemia who had triglyceride levels >500 mg/dl despite conventional triglyceride lowering therapy

 

Mean ±SD

Percentile

25th

Median

75th

Age (years)

50 ±7

44

50

54

TG (mg/dl)

1251 ± 671

791

884

1640

Total cholesterol (mg/dl)

303 ± 107

231

253

373

HDLC (mg/dl)

29 ± 9

24

27

36

Non-HDLC (mg/dl)

274 ± 104

200

228

347

APOE genotype

2-3

2-4

3-3

3-4

Responders n=12

2 (17%)

1 (8%)

6 (50%)

3 (25%)

Non-responders n=3

0

0

0

3 (100%)

Total n=15

2/15 (13%)

1/15 (7%)

6/15 (40%)

6/15 (40%)

  1. APOE 3–4 was more common in non-responders, Fisher’s p=. 04.