Lipids in Health and Disease

Table 1 Biochemical parameters in the presence and absence of minor alleles

From: The I405V and Taq1B polymorphisms of the CETP gene differentially affect sub-clinical carotid atherosclerosis

Parameters	A. I405V Genotypes
	II	V carriers	p value ≤
	(n=32-59)	(n=70-148)
Frequency (%)	29	71
CETP (%)	14.5 ± 9.0	11.0 ± 7.2	0.015
HDL-C (mg/dL)	72 ± 24	74 ± 18	0.192
HDL ₂ -C (mg/dL)	15 ± 6	17 ± 6	0.030
PLTP (%)	22.3 ± 11.9	15.8 ± 9.9	0.001
Lipoprotein (a) (mg/dL)	27 ± 30	32 ± 36	0.477
OxLDL Ab (OD)	0.33 ± 0.16	0.38 ± 0.19	0.405
Parameters	B. Taq1B Genotypes
	B1B1	B2 carriers	p value ≤
	(n=32-68)	(n=70-139)
Frequency (%)	33	67
CETP (%)	13.4 ± 8.2	11.3 ± 7.7	0.103
HDL-C (mg/dL)	74 ± 26	73 ± 16	0.584
HDL₂-C (mg/dL)	17 ± 6	17 ± 5	0.657
PLTP (%)	17 ± 11	18 ± 11	0.860
Lipoprotein (a) (mg/dL)	24 ± 30	33 ± 36	0.014
oxLDL Ab (OD)	0.33 ± 0.17	0.38 ± 0.18	0.230

Data are presented as means ± standard deviation; (sample number): n = minimum and maximum of subjects with determined parameters; p values: Mann–Whitney U test for comparisons between the presence and absence of the minor alleles (V and B2). Significant differences: p≤0.05 in bold. CETP (%) = activity of cholesterol ester transfer protein; HDL-C = high-density lipoprotein cholesterol; PLTP (%) = activity of phospholipid transfer protein; oxLDL Ab = antibodies against oxidized LDL titers; (OD)= optical density.

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