Comparative evaluation of flavone from Mucuna pruriens and coumarin from Ionidium suffruticosum for hypolipidemic activity in rats fed with high Fat diet

Table 1 Average Body weight changes in control and experimental rats

Groups	Initial Weight (g)	Final Weight (g)	Average Body weight gain (g)
Group I	137.34±0.47^bNS	156.66±2.47^b*	19.32±2.39^b*
Group II	136.33±0.42^aNS	198.64±2.58^a*	62.31±1.90^a*
Group III	136.71±0.41^aNS,bNS	162.33±2.16^aNS,b**	25.62±2.54^{aNS, b*}
Group IV	136.57±0.53^aNS,bNS	161.26±1.38^aNS,b*	24.69±3.28^aNS,b*
Group V	137.55±0.74^aNS,bNS	161.51±1.74^aNS,b*	23.96±3.39 ^aNS,b*

Values are expressed as mean ± SE (n=6 rats); P values: *<0.001, **<0.05; NS: Non significant; a → group I compared with groups II, III, IV& V; b → group II compared with groups III, IV& V; Group I : Standard chow diet (Control); Group II : High Fat Diet (Negative Control); Group III : HFD + Flavone (M.pruriens) (10mg/kg b.wt); Group IV : HFD+Coumarin (I. suffruticosum) (10mg/kg b.wt); Group V : HFD + Atorvastatin (1.2 mg/kg b.wt) (Positive Control).

ISSN: 1476-511X