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Table 3 Serum LDL cholesterol levels in habitual alcohol consumption groups by Mt5178 C/A genotype

From: Joint effect of longevity-associated mitochondrial DNA 5178 C/A polymorphism and alcohol consumption on risk of hyper-LDL cholesterolemia in middle-aged Japanese men

 

Alcohol consumption

P for trend

 

Non- or ex-drinkers

Occasional drinkers

Daily drinkers

 

Mt5178C

N = 44

N = 84

N = 111

 

LDL cholesterol

135.0 ± 5.2

120.5 ± 3.7

117.1 ± 3.3*

0.007

LDL cholesterol †

135.8 ± 5.2

120.4 ± 3.8

116.9 ± 3.3**

0.005

LDL cholesterol ‡

135.6 ± 6.3

119.5 ± 4.9*

116.4 ± 4.1**

0.006

Mt5178A

N = 21

N = 60

N = 74

 

LDL cholesterol

121.4 ± 6.7

118.5 ± 4.0

116.5 ± 3.6

0.506

LDL cholesterol †

122.1 ± 6.7

118.4 ± 3.9

116.3 ± 3.5

0.445

LDL cholesterol ‡

121.4 ± 7.5

117.6 ± 5.1

116.1 ± 4.7

0.502

  1. LDL: low-density lipoprotein. †LDL cholesterol levels are given as least-square means ± S.E. adjusted for age and body mass index; ‡LDL cholesterol levels are given as least-square means ± S.E. adjusted for age, body mass index, habitual smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was applied. *P < 0.05 vs. Non- or ex-drinkers with Mt5178C; **P < 0.01 vs. Non- or ex-drinkers with Mt5178C.
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Lipids in Health and Disease

ISSN: 1476-511X